The inner envelope provides you with an opportunity to clarify who is invited, since only those mentioned on the inner envelope are intended guests. Here it’s fine to refer to guests as you would in a social setting, including the children that are invited to the wedding.

outer: Dr. and Mrs. Nathaniel Powers
inner: Aunt Paula and Uncle Nate

outer: Mr. and Mrs. Thomas Higgins
inner: Mr. and Mrs. Higgins
Carrie Higgins
Carter Higgins

outer: John Lewis and Helena Rawlingson
inner: John and Helena

outer: Miss Sally Peters
inner: Sally

outer: Mr. Peter Levinson
inner: Peter and Guest

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Posted in: Etiquette, Envelope addressing etiquette